Monday, August 2, 2010

Microsomal Enzyme System (MES) - Use it or Lose it

With summer vacation coming up I'm wondering just how fit my MES is.  Responsible for detoxifying lots of stuff, including my favorite Lemon Hart & Sons rum (original supplier to the British Navy, dating back to the 18th century), your Microsomal Enzyme System resides in the smooth-surfaced endoplasmic reticulum of the liver - as opposed to the rough-surfaced endoplasmic reticulum which is primarily engaged in enzymatic protein synthesis.  Your MES is a sort of "use it or lose it" part of the body.  Unless occasionally stimulated, it atrophies and becomes useless.  (Need I say get your mind out of the gutter, once again.)  Your MES may partially explain why almost all centenarians claim that their longevity is the result of exercise, lots of veggies and a wee nip of spirits every day.  Hepatic health is important therefore, and not only to us who occasionally imbibe.  Of course, you don't want to overwhelm your liver or you may also expire prematurely via cirrhosis.  The critical point then, is to stimulate, but not over- or under-stimulate your MES.  Hmmm ... hope I've got just the right medicinal intake level ... don't want to err on the low side ... more fun to err on the upside ... hmmm